Delay discounting predicts cigarette smoking in a laboratory model of abstinence reinforcement
Delay discounting predicts cigarette smoking in a laboratory model of abstinence reinforcement
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DOI：
10.1007/s00213-006-0627-5
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发表时间：
2007-03-01
影响因子：
3.4
通讯作者：
Raiff, Bethany R.
中科院分区：
文献类型：
--
作者：
Dallery, Jesse;Raiff, Bethany R.
较高的延迟折扣率或冲动选择可能与戒烟强化干预期间的复发有关，透皮尼古丁贴片可能会减弱延迟折扣。目的在实验室戒烟强化模型中评估尼古丁剥夺后延迟折扣与吸烟的关系，以及透皮尼古丁贴片对延迟折扣和吸烟的影响。材料和方法没有自我报告戒烟意图的吸烟者被随机分配到活性（14毫克）或安慰剂贴片组（每组n = 15）。在3个小时的剥夺期后，参与者完成延迟折扣任务、情绪和渴望测量，最后进行禁欲强化的实验室模型。三种戒断强化条件在三个疗程中以平衡的顺序呈现。在对照组中，无论是否吸烟，每隔30秒就发放一次财务结果。在低（5美元）和高（20美元）阶段，参与者每禁欲30秒就能赚到越来越多的钱。结果低、高条件组吸烟潜伏期明显高于对照组，吸烟量明显减少。尼古丁贴片减少了负面影响，但对延迟折扣或吸烟没有显著影响。在低和高条件下吸烟的个体显示出更高的折扣率。结论：该贴片不能减少延迟折扣或剥夺一段时间后的吸烟，但偶然的戒烟显著减少吸烟。在戒断强化治疗模型中，较高的延迟折扣率与吸烟有关。
Rationale Higher rates of delay discounting, or impulsive choice, may be related to relapse during abstinence reinforcement interventions for cigarette smoking, and a transdermal nicotine patch may attenuate delay discounting.Objective The objectives of this study are to assess the relation between delay discounting and smoking after nicotine deprivation in a laboratory model of abstinence reinforcement and the effects of a transdermal nicotine patch on discounting and smoking.Materials and Methods Smokers with no self-reported intention to quit were randomly assigned to an active (14 mg) or placebo patch group (n = 15 per group). In each of three sessions, after a 3-h deprivation period, participants completed a delay discounting task, mood, and craving measures and finally engaged in a laboratory model of abstinence reinforcement. Three abstinence reinforcement conditions were presented in counterbalanced order across the three sessions. During the control session, monetary consequences were delivered every 30 s regardless of smoking. During the low ($5.00 available) and high ($20.00 available) sessions, participants could earn a progressively increasing amount of money for each 30 s period of abstinence.Results The low and high conditions significantly increased the latency to smoke relative to control and significantly decreased the amount of smoking. The nicotine patch decreased negative affect, but it did not significantly affect delay discounting or smoking. Individuals who smoked during the low and high conditions showed higher rates of discounting.Conclusions The patch did not attenuate delay discounting or smoking after a period of deprivation, but contingencies for abstinence significantly decreased smoking. Higher rates of delay discounting were related to smoking in a model of abstinence reinforcement treatment.