Retention enhancement by pre-test beta-endorphin and oxotremorine and its reversal by scopolamine.
Retention enhancement by pre-test beta-endorphin and oxotremorine and its reversal by scopolamine.
复制标题
预测试β-内啡肽和氧化震颤素增强保留，东莨菪碱逆转保留。
DOI：
10.1016/s0163-1047(88)90922-3
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Izquierdo,I
中科院分区：
文献类型：
--
作者：
Brioni,JD;Izquierdo,I
试验前给药-内啡肽（0.05微克/只）、倍半马酸氧tremorine sesquifumarate（5.0微克/只）或-内啡肽加氧tremorine可增强小鼠条件情绪反应的保留测试表现。这种作用被东莨菪碱阻断。东莨菪碱本身没有效果。这些数据表明-内啡肽引起的保留增强可能涉及胆碱能机制的二次激活。
The pre-test administration of beta-endorphin (0.05 microgram/mouse), oxotremorine sesquifumarate (5.0 micrograms/mouse), or beta-endorphin plus oxotremorine enhanced retention test performance of a conditioned emotional response in mice. The effects were blocked by scopolamine. Scopolamine had no effect of its own. The data suggest that the retention enhancement caused by beta-endorphin may involve the secondary activation of cholinergic mechanisms.