The ASTRAL compendium for protein structure and sequence analysis

The ASTRAL compendium for protein structure and sequence analysis
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DOI:
10.1093/nar/28.1.254
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发表时间:
2000-01-01
影响因子:
14.9
通讯作者:
Levitt, R
Levitt, R
中科院分区:
生物学2区
文献类型:
--
作者:
Brenner, SE;Koehl, P;Levitt, R

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ASTRAL纲要提供了几个数据库和工具来帮助分析蛋白质结构,特别是通过使用它们的序列。系统中包含的SPACI分数总结了蛋白质结构的总体特征。PDB序列图谱文件提供了所研究分子的氨基酸序列(数据库条目中的SEQRES记录)和在结构中实验观察到的原子序列(ATOM记录)之间的联系。这些图谱与SCOP数据库中的信息相结合,提供蛋白质结构域的序列。领域数据库的选定子集,用几种不同的方法测量了不同程度的相似性,也可用。ASTRAL可通过http://astral.stanford.edu/访问。
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. The SPACI scores included in the system summarize the overall characteristics of a protein structure. A structural alignments database indicates residue equivalencies in superimposed protein domain structures, The PDB sequence-map files provide a linkage between the amino acid sequence of the molecule studied (SEQRES records in a database entry) and the sequence of the atoms experimentally observed in the structure (ATOM records). These maps are combined with information in the SCOP database to provide sequences of protein domains. Selected subsets of the domain database, with varying degrees of similarity measured in several different ways, are also available. ASTRAL may be accessed at http://astral.stanford.edu/.