The Clinical Importance of the Heterogeneity of HER2 neu.
The Clinical Importance of the Heterogeneity of HER2 neu.
复制标题
HER2 neu 异质性的临床重要性。
DOI：
10.1159/000319020
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发表时间：
2010-07-24
影响因子：
0.8
通讯作者：
Amazon, Kip
中科院分区：
文献类型：
--
作者：
Davila, Enrique;Amazon, Kip
我们报告一例乳腺癌患者，免疫组织化学显示肿瘤区域3+阳性，而HER2-neu阴性，彼此相邻。根据测试区域的不同，结果完全不同。这一研究具有重要的临床意义。我们建议在所有最初检测结果为阴性的病例中重新检测大部分肿瘤。
We report on a patient with breast cancer in whom there were areas of the tumor that were 3+ positive and negative for HER2 neu by immunohistochemistry, adjacent to each other. Depending on the area tested the results were completely different. The clinical implications are important. We recommend retesting a large portion of the tumor in all cases of initially negative test results.