Sexual Orientation Differences in Alcohol Use Disorder Across the Adult Life Course

Sexual Orientation Differences in Alcohol Use Disorder Across the Adult Life Course
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DOI:
10.1016/j.amepre.2020.04.012
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发表时间:
2020-09-01
影响因子:
5.5
通讯作者:
Exten, Cara
Exten, Cara
中科院分区:
医学2区
文献类型:
--
作者:
Fish, Jessica N.;Exten, Cara

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引言:酒精使用障碍中与性取向相关的差异是公认的。然而,酒精使用障碍的性取向差异在整个生命过程中的变化程度却知之甚少。也有一个有限的了解如何暴露于少数民族的压力和他们的关系与酒精使用障碍的变化作为一个功能的年龄。方法:使用2012-2013年收集的全国代表性数据,作者使用性别分层时变效应模型来估计18-60岁的异性恋和性少数成年人(N= 28,090)中酒精使用障碍的年龄特异性患病率。在性少数成年人(n= 1,050)中,作者还评估了暴露于女同性恋,男同性恋和双性恋相关歧视与酒精使用障碍之间的年龄相关性。分析于2019年进行。结果:18-45岁的男同性恋和双性恋男性参与者表现出最高的酒精使用障碍患病率(例如,25岁时>45%),而女同性恋、男同性恋和双性恋女性参与者最有可能在45至55岁之间达到酒精使用障碍的标准。在过去一年中经历过歧视的性少数成年人在23岁至34岁之间以及42岁至53岁之间患酒精使用障碍的几率更大;歧视与酒精使用障碍之间的关联在性少数男性中最强。酒精使用障碍中与性取向相关的差异在整个生命过程中是动态的,并指出筛查和干预的关键时刻。性少数群体健康不平等的发展前景需要集中研究的关注,因为研究结果将有助于确定在生命过程中不同阶段促进性少数群体健康的战略。(C)2020年美国预防医学杂志。爱思唯尔公司出版All rights reserved.
Introduction: Sexual orientation-related disparities in alcohol use disorder are well-established. Yet, the degree to which sexual orientation differences in alcohol use disorder vary across the life course is poorly understood. There is also a limited understanding of how exposure to minority stressors and their relationship with alcohol use disorder vary as a function of age.Methods: Using nationally representative data collected in 2012-2013, authors used sex-stratified time-varying effect models to estimate age-specific prevalence rates of alcohol use disorder among heterosexual and sexual minority adults aged 18-60 years (N=28,090). Among sexual minority adults ( n=1,050), authors also assessed age-specific associations between exposure to lesbian, gay, and bisexual-related discrimination and alcohol use disorder. Analyses were conducted in 2019.Results: Gay and bisexual male participants aged 18-45 years demonstrated the highest prevalence rates of alcohol use disorder (e.g., >45% at age 25 years), whereas lesbian, gay, and bisexual female participants were most likely to meet the criteria for alcohol use disorder between ages 45 and 55 years. Sexual minority adults who experienced discrimination in the past year had greater odds of alcohol use disorder between ages 23 and 34 years and again from ages 42 to 53 years; the association between discrimination and alcohol use disorder was strongest among sexual minority men.Conclusions: Sexual orientation-related disparities in alcohol use disorder are dynamic across the life course and point to critical times for screening and intervention. Developmental perspectives of sexual minority health inequities demand focused research attention as findings will help to identify strategies for promoting sexual minority health at distinct points in the life course. (C) 2020 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.