Recruiting children into cancer trials--role of the United Kingdom Children's Cancer Study Group (UKCCSG).
Recruiting children into cancer trials--role of the United Kingdom Children's Cancer Study Group (UKCCSG).
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招募儿童参加癌症试验 - 英国儿童癌症研究小组（UKCCSG）的角色。
DOI：
10.1038/sj.bjc.6600990
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发表时间：
2003-06-02
影响因子：
8.8
通讯作者：
中科院分区：
文献类型：
--
作者：
英国儿童癌症研究小组（UKCCSG）成立于1977年，为服务提供和研究提供了一个高度组织化的结构，代表了成人癌症社区目前所追求的模式。由于儿童癌症是如此罕见，因此将绝大多数儿童转介到专家中心网络中，并将最大数量的儿童招募到国家和国际临床试验中，既是必要的，也是可行的。在过去的30-40年里，治疗取得了重大进展，现在大约70%被诊断患有癌症的儿童将被治愈。然而，在这一患者群体中进行临床试验确实会引起一些具体问题，这些问题将在本文中讨论。
The UK Children's Cancer Study Group (UKCCSG), established in 1977, provides a highly organised structure for both service provision and research, and represents the model to which the adult cancer community is currently aspiring. Since childhood cancer is so rare, it is both essential and feasible for the vast majority of children to be referred into the network of specialist centres, and also for the maximum number of children to be recruited into national and international clinical trials. Over the last 30–40 years there have been major advances in treatment, such that now approximately 70% of children diagnosed with cancer will be cured of their disease. The conduct of clinical trials in this patient population does, however, raise a number of specific issues and these are discussed in the paper.