Seasonal variation of salivary testosterone in men, normally cycling women, and women using hormonal contraceptives.
Seasonal variation of salivary testosterone in men, normally cycling women, and women using hormonal contraceptives.
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男性、正常骑自行车的女性和使用激素避孕药的女性唾液睾酮的季节性变化。
DOI：
10.1016/j.physbeh.2011.07.009
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发表时间：
2011
影响因子：
2.9
通讯作者：
Huettel,ScottA
中科院分区：
文献类型：
--
作者：
Stanton,StevenJ;Mullette-Gillman,O'DhanielA;Huettel,ScottA
人类的内源性睾酮浓度在许多时间尺度上变化，对超过每月周期的变化知之甚少。过去的季节性或年际变化的研究主要使用男性参与者，并产生了不一致的结果。因此，很少有人知道睾丸激素浓度如何在一年中波动，这种变化是否在男性和女性之间存在差异，以及是否有激素避孕药使用的影响。本研究从男性和女性的大样本（N=718）中收集唾液样本，每个样本在一个完整的日历年内相对均匀分布的一个时间点收集。男性和正常骑自行车的女性都表现出唾液睾酮浓度的季节性变化，例如睾酮浓度在秋季最高，夏季最低。值得注意的是，正常骑自行车的女性的睾丸激素浓度在秋季最高时比夏季最低时高出100%以上。使用激素避孕药的女性不仅内源性睾酮浓度持续较低，而且还表现出更平坦的季节性睾酮分布。心理学和人类行为内分泌学的研究的影响进行了讨论。
Humans' endogenous testosterone concentrations vary over a number of temporal scales, with little known about variation longer than monthly cycles. Past studies of seasonal or circannual variation have principally used male participants and have produced inconsistent results. Thus, little is known about how testosterone concentrations fluctuate throughout the year, whether such variation differs between men and women, and whether there are influences of hormonal contraceptive use. The present study collected saliva samples from a large sample (N=718) of men and women, each collected at one time point within a relatively uniform distribution over a full calendar year. Both men and normally-cycling women displayed seasonal variation in salivary testosterone concentrations, such that testosterone concentrations are maximal in the fall and minimal in the summer. Notably, normally-cycling women had testosterone concentrations that were over 100% greater at their maximum in fall compared to their minimum in summer. Women using hormonal contraceptives not only had consistently lower endogenous testosterone concentrations, but also showed a flatter seasonal testosterone profile. The implications for studies of psychology and human behavioral endocrinology are discussed.