Lifetime Prevalence and Correlates of Schizophrenia-Spectrum, Affective, and Other Non-affective Psychotic Disorders in the Chinese Adult Population
Lifetime Prevalence and Correlates of Schizophrenia-Spectrum, Affective, and Other Non-affective Psychotic Disorders in the Chinese Adult Population
复制标题
DOI：
10.1093/schbul/sbx056
复制
发表时间：
2017-11-01
影响因子：
6.6
通讯作者：
Bebbington, Paul
中科院分区：
文献类型：
--
作者：
Chang, Wing Chung;Wong, Corine Sau Man;Bebbington, Paul
精神障碍的终生患病率在不同的研究中差异很大。流行病学调查很少检查除精神分裂症以外的特定精神障碍的患病率，并且大多数使用单相设计，而没有使用临床重新评估访谈来进行诊断验证。本研究基于全港性、以人口为基础的家庭精神障碍调查，调查了16-75岁的中国社区居民（N = 5719）中精神分裂症谱系、情感性和其他非情感性精神障碍的终生患病率、相关因素和服务利用率。调查采用两阶段设计，包括第一阶段精神病筛查和第二阶段诊断验证，结合来自精神科医生半结构化访谈和病历回顾的临床信息，以确定DSM-IV对精神障碍的终身诊断。收集了社会人口学、心理社会特征和服务利用的数据。我们的研究结果显示，总体精神障碍的终生患病率为2.47%，精神分裂症为1.25%，妄想障碍为0.15%，未指明精神障碍为0.38%，双相情感障碍合并精神障碍为0.31%，抑郁症合并精神障碍为0.33%。精神分裂症谱系障碍与精神病家族史、吸烟和表明社会经济劣势的变量有关。受害经历与情感性精神病和其他非情感性精神病显著相关。在过去的一年里，大约80%患有精神疾病的参与者都曾就精神健康问题寻求过某种专业帮助。使用包括访谈和记录数据的综合诊断评估，我们的结果表明，大约2.5%的中国成年人终生患有精神障碍，这是一个主要的公共卫生问题。
Lifetime prevalence of psychotic disorders varies widely across studies. Epidemiological surveys have rarely examined prevalences of specific psychotic disorders other than schizophrenia, and the majority used a single-phase design without employing clinical reappraisal interview for diagnostic verification. The current study investigated lifetime prevalence, correlates and service utilization of schizophrenia-spectrum, affective, and other non-affective psychotic disorders in a representative sample of community-dwelling Chinese adult population aged 16-75 years (N = 5719) based on a territory-wide, population-based household survey for mental disorders in Hong Kong. The survey adopted a 2-phase design comprising first-phase psychosis screening and second-phase diagnostic verification incorporating clinical information from psychiatrist-administered semi-structured interview and medical record review to ascertain DSM-IV lifetime diagnosis for psychotic disorders. Data on sociodemographics, psychosocial characteristics and service utilization were collected. Our results showed that lifetime prevalence was 2.47% for psychotic disorder overall, 1.25% for schizophrenia, 0.15% for delusional disorder, 0.38% for psychotic disorder not otherwise specified, 0.31% for bipolar disorder with psychosis, and 0.33% for depressive disorder with psychosis. Schizophrenia-spectrum disorder was associated with family history of psychosis, cigarette smoking and variables indicating socioeconomic disadvantage. Victimization experiences were significantly related to affective psychoses and other non-affective psychoses. Around 80% of participants with any psychotic disorder sought some kind of professional help for mental health problems in the past year. Using comprehensive diagnostic assessment involving interview and record data, our results indicate that approximately 2.5% of Chinese adult population had lifetime psychotic disorder which represents a major public health concern.