Ischemic infarcts of the choroid (Elschinig spots). A cause of retinal separation in hypertensive disease with renal insufficiency. A clinical and histopathologic study.
Ischemic infarcts of the choroid (Elschinig spots). A cause of retinal separation in hypertensive disease with renal insufficiency. A clinical and histopathologic study.
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脉络膜缺血性梗塞（Elschinig 斑）。
DOI：
10.1016/0002-9394(68)90815-5
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发表时间：
1968
影响因子：
4.2
通讯作者：
B. Klien
中科院分区：
文献类型：
--
作者：
B. Klien;B. Klien
作者2报道，视网膜分离作为一种眼部并发症，与肾功能不全的全身性高血压密切相关，可能并不像文献中罕见的报告所暗示的那样罕见。它最常在高血压神经视网膜病的末期遇到，只要可以进行临床和组织病理学发现的相关研究，通常就会发现它与全身性疾病的末期变化有关。然而，随着器官移植技术的改进，肾切除和肾移植后严重肾功能不全的恢复可能会变得更加常见，如Buchanan和Ellis1最近报道的，这证明了人们对此类视网膜分离的发病机制和治疗的新兴趣（Lapco，Weiler和Greene。2 Bosco3）。临床上，这种类型的视网膜分离通常是双侧的，非孔源性的，通常是多房性的，大疱性的和极其光滑的，它的首次出现经常出现在外围。与其他次要脱离一样，它具有容易移动的趋势，并且在其行进的高度时，它通常占据眼底的下半部分。随着患者从基础疾病中恢复，这种情况是可逆的，并且在病情恶化时可能会复发。治疗必须针对全身性疾病。人们已经认识到，脱离的形成和可逆性与血压的高度或氮质血症的程度没有直接关系。拉普科和他的同事
Retinal separation as an ocular complica-authors2 reported a close association with di tion of systemic hypertension with renal insufficiency is probably not as rare as the infrequent reports in the literature imply. It is most often encountered in the terminal stages as part of a hypertensive neuroretinopathy, and whenever correlated studies of the clinical and histopathologic findings are possible, it usually is found to concern the terminal variety of systemic disease. However, with improving techniques of organ transplantation, recovery from severe renal insufficiency after nephrectomy and kidney transplants, such as Buchanan and Ellis1 reported recently, may become more common, justifying the renewed interest in the pathogenesis and therapy of this type of retinal separation (Lapco, Weiler and Greene. 2 Bosco3).Clinically, this type of retinal separation is usually bilateral, nonrhegmatogenous, often multilocular, bullous and extremely smooth, with its first appearance frequently in the periphery. Like other secondary detachments it has a tendency to shift readily, and at the height of its course it commonly occupies the inferior half of the fundus. It is reversible with recovery of the patient from the underlying disease and may recur on its exacerbations. Therapy must be directed toward the systemic disease. It has been recognized that formation and reversibility of the detachment are not directly related to height of blood pressure or degree of azotemia. Lapco and his co-