Changes in EGF concentrations during estrous cycle in bovine endometrium and their alterations in repeat breeder cows
Changes in EGF concentrations during estrous cycle in bovine endometrium and their alterations in repeat breeder cows
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DOI：
10.1016/j.theriogenology.2003.08.019
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发表时间：
2004-07-01
期刊：
影响因子：
2.8
通讯作者：
Takahashi, Y
中科院分区：
文献类型：
--
作者：
Katagiri, S;Takahashi, Y
本研究的目的是确定子宫内膜EGF浓度的周期性变化异常是否可以作为重复育种奶牛的诊断工具。首先，在发情周期中的EGF浓度的配置文件确定使用子宫内膜组织从31荷斯坦奶牛屠宰后。周期性奶牛有两个EGF浓度的峰值。然后，在同一发情周期的第3、7和14天，通过活检从12头对照母牛和20头重复繁殖母牛获得子宫内膜组织。子宫内膜EGF浓度活检样本的控制是类似的屠宰场材料中发现的，他们是高的第3和14天（9.2和10.4纳克/克组织，分别）和低的第7天（3.8纳克/克组织）。EGF浓度在重复繁殖母牛有不同的配置文件;他们是相似的，在第3天，第7天和第14天（4.4，3.4和4.0 ng/g组织，分别）。总之，子宫内膜EGF浓度的变化在重复育种改变，这些改变可能是一个潜在的诊断标记重复育种奶牛。(C)2003年爱思唯尔公司All rights reserved.
The objective of the present study was to determine if abnormalities in the cyclic changes of endometrial EGF concentrations can be a diagnostic tool for repeat breeder cows. First, the profile of EGF concentrations during the estrous cycle was determined using endometrial tissues obtained from 31 Holstein cows after slaughter. Cyclic cows had two peaks of EGF concentrations. Then, endometrial tissues were obtained from 12 control and 20 repeat breeder cows by biopsy on Days 3, 7, and 14 of the same estrous cycle. Endometrial EGF concentrations in biopsied samples of the controls were similar to those found in slaughterhouse materials; they were high on Days 3 and 14 (9.2 and 10.4 ng/g tissue, respectively) and low on Day 7 (3.8 ng/g tissue). Concentrations of EGF in repeat breeder cows had a different profile; they were similar on Days 3, 7, and 14 (4.4, 3.4, and 4.0 ng/g tissue, respectively). In conclusion, changes in endometrial EGF concentrations were altered in repeat breeders; these alterations may be a potential diagnostic marker for repeat breeder cows. (C) 2003 Elsevier Inc. All rights reserved.