Lemierre syndrome presenting as acute mastoiditis in a 2-year-old girl with congenital dwarfism
Lemierre syndrome presenting as acute mastoiditis in a 2-year-old girl with congenital dwarfism
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DOI：
10.4081/idr.2015.5922
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发表时间：
2015-01-01
影响因子：
3.2
通讯作者：
Warrier, Kavita
中科院分区：
文献类型：
--
作者：
Fischer, Jason B.;Prout, Andrew;Warrier, Kavita
Lemierre综合征是由梭杆菌属引起的颈内静脉脓毒性血栓性静脉炎。从历史上看，这些感染起源于口咽，通常见于年龄较大的儿童，青少年和年轻人。最近，耳源性来源在年幼的儿童已被描述的频率越来越高。我们提出一个2岁的孩子，谁最初开发中耳炎与鼓膜穿孔，并继续发展乳突炎和非闭塞性血栓形成的静脉窦和右颈内静脉。坏死梭杆菌从乳突的手术培养物中生长，随后的计算机断层扫描显示颈内静脉闭塞，患者成功接受克林霉素、环丙沙星和依诺肝素治疗。这个病例证明了在耳源性感染中考虑梭杆菌的重要性，当F。已识别坏死组织。
Lemierre syndrome is defined by septic thrombophlebitis of the internal jugular vein caused by Fusobacterium. Historically, these infections originate from the oropharynx and typically are seen in older children, adolescents and young adults. More recently, otogenic sources in younger children have been described with increasing frequency. We present a case of a two-year old, who initially developed an otitis media with perforation of the tympanic membrane and went on to develop mastoiditis and non-occlusive thrombosis of the venous sinus and right internal jugular vein. Fusobacterium necrophorum was grown from operative cultures of the mastoid, ensuing computed tomography scan revealed occlusion of the internal jugular vein and the patient was successfully treated with clindamycin, ciprofloxacin and enoxaparin. This case demonstrates the importance of considering Fusobacterium in otogenic infections and the consideration of Lemierre syndrome when F. necrophorum is identified.