DAS-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis

DAS-driven therapy versus routine care in patients with recent-onset active rheumatoid arthritis
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DOI:
10.1136/ard.2008.097683
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发表时间:
2010-01-01
影响因子:
27.4
通讯作者:
Dijkmans, B. A. C.
Dijkmans, B. A. C.
中科院分区:
医学1区
文献类型:
--
作者:
Goekoop-Ruiterman, Y. P. M.;de Vries-Bouwstra, J. K.;Dijkmans, B. A. C.

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目的:比较疾病活动评分(DAS)驱动疗法和常规护理在新近发病的类风湿关节炎患者中的疗效。方法:新近发病的类风湿关节炎患者接受传统抗风湿疗法的最佳研究、比较不同治疗策略的随机对照试验(A组)或两个早期关节炎门诊(B组)。在A组,系统的DAS驱动的治疗调整旨在实现较低的疾病活动度(DAS
Objectives: To compare the efficacy of Disease Activity Score (DAS)-driven therapy and routine care in patients with recent-onset rheumatoid arthritis.Methods: Patients with recent-onset rheumatoid arthritis receiving traditional antirheumatic therapy from either the BeSt study, a randomised controlled trial comparing different treatment strategies (group A), or two Early Arthritis Clinics (group B) were included. In group A, systematic DAS-driven treatment adjustments aimed to achieve low disease activity (DAS