Electrocatalytic oxidation and determination of insulin at CNT-nickel-cobalt oxide modified electrode
Electrocatalytic oxidation and determination of insulin at CNT-nickel-cobalt oxide modified electrode
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DOI：
10.1016/j.snb.2010.08.004
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发表时间：
2010-10-28
影响因子：
8.4
通讯作者：
Virtanen, Vesa
中科院分区：
文献类型：
--
作者：
Arvinte, Adina;Westermann, A. Caroline;Virtanen, Vesa
将镍钴氧化物粉末与碳纳米管直接复合，制备了碳纳米管镍钴氧化物/NaNation复合材料，并将其沉积在丝网印刷电极衬底上，用循环伏安和安培技术研究了它们在NaOH和磷酸盐缓冲溶液中的电化学行为。从灵敏度、检测限和对胰岛素检测的稳定性等方面评价了这些传感器的电催化活性。CNT-镍钴氧化物/NaNation电极能够在生理pH条件下对水溶液中的胰岛素进行氧化检测，具有良好的灵敏度(2 2 5 7mU A x mg(-1)x mL(-1))和传感器在碱性溶液中的电化学活化步骤已被证明是碳纳米管-镍-氧化钴-复合电极对胰岛素检测的三倍灵敏响应所必需的(C)2010 Elsevier BV版权所有
CNT-nickel-cobalt oxide/Nation composites were prepared by combining the nickel-cobalt oxide powder with CNT directly into the Nation solution used as a binder and deposited on screen-printed electrodes substrates Their electrochemical behaviour was investigated by means of cyclic voltammetry and amperometry techniques in NaOH and phosphate buffer solutions The electrocatalytic activity of these sensors was evaluated in terms of sensitivity detection limit and stability towards insulin detection CNT-nickel-cobalt oxide/Nation electrodes enable the oxidative detection of insulin in aqueous solution at physiological pH with a good sensitivity (22 57 mu A x mg(-1) x mL(-1)) An electrochemical activation step of the sensor in alkaline solution has been shown to be necessary for a three times more sensitive response of CNT-nickel-cobalt oxide-composite electrode toward insulin detection (c) 2010 Elsevier BV All rights reserved