CONFAC: automated application of comparative genomic promoter analysis to DNA microarray datasets
CONFAC: automated application of comparative genomic promoter analysis to DNA microarray datasets
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DOI：
10.1093/nar/gkh353
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发表时间：
2004-07-01
影响因子：
14.9
通讯作者：
Moreno, CS
中科院分区：
文献类型：
--
作者：
Karanam, S;Moreno, CS
DNA微阵列技术的出现和多种脊椎动物基因组的测序为比较基因组学与高通量基因表达分析的整合提供了独特的机会。在这里，我们描述了保守转录因子结合位点（CONFAC）软件，其能够一次高通量地鉴定数百个基因的调控区中的保守转录因子结合位点（TFBS）（morenolab.whitehead.emory.edu/cgi-bin/confac/login.pl
The advent of DNA microarray technology and the sequencing of multiple vertebrate genomes has provided a unique opportunity for the integration of comparative genomics with high-throughput gene expression analysis. Here we describe the conserved transcription factor binding site (CONFAC) software that enables the high-throughput identification of conserved transcription factor binding sites (TFBSs) in the regulatory regions of hundreds of genes at a time (http://morenolab.whitehead.emory.edu/cgi-bin/confac/login.pl