Genetics of morphological traits and inherited disorders.

Genetics of morphological traits and inherited disorders.
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形态特征和遗传性疾病的遗传学。

DOI:
10.1079/9780851995205.0087
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发表时间:
1999
期刊:
影响因子:
--
通讯作者:
A. Ruvinsky
A. Ruvinsky
中科院分区:
--
文献类型:
--
作者:
F. Nicholas;M. Rothschild;A. Ruvinsky

文献摘要

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与其他主要驯养动物物种相比,人们对马形态特征和遗传性疾病的遗传知之甚少,主要是因为研究马遗传模式的成本相对较高且时间较长。然而,已经取得了一些重要的发现,尤其是近年来在分子水平上的发现。本章的主要目的是总结马的形态特征和有大量单基因遗传证据的遗传性疾病。还简要提及了其他性状,这些性状有强有力的证据表明存在家族性,但尚未建立单基因座遗传。关于与毛色相关的遗传性疾病的进一步讨论将在第 3 章中进行,有关其他遗传性疾病的更多详细信息可在第 8 章中找到。随着分子革命目前如火如荼地进行,特别是随着覆盖所有牛染色体所有区域的基因标记的发展(见第 10 章),关于马形态性状和疾病遗传的知识将在未来几十年迅速增加。如下所述,有关本章主题的定期更新信息可在 Internet 上获得。通过这种方式,读者可以
Less is known about the inheritance of morphological traits and inherited disorders in horses than in the other major domesticated animal species, primarily because of the relatively high cost and long time involved in investigating inheritance patterns in horses. However, some important discoveries have been made, most notably at the molecular level in recent years. The main aim of this chapter is to present a summary of equine morphological traits and inherited disorders for which there is substantial evidence of single-gene inheritance. A brief mention is also made of other traits for which there is strong evidence of familial occurrence, but for which single-locus inheritance has not been established. Further discussion on inherited disorders associated with coat colour is presented in Chapter 3, and additional detail on other inherited disorders can be found in Chapter 8. With the molecular revolution now in full swing, and, in particular, with the development of gene markers covering all regions of all bovine chromosomes (see Chapter 10), knowledge of the inheritance of morphological traits and disorders in horses will increase rapidly in the decades ahead. As described below, regularly updated information on the subject matter of this chapter is available on the Internet. By this means, it is possible for readers