The Long-term Patency of Lymphaticovenular Anastomosis in Breast Cancer–Related Lymphedema
The Long-term Patency of Lymphaticovenular Anastomosis in Breast Cancer–Related Lymphedema
复制标题
乳腺癌相关淋巴水肿淋巴管小静脉吻合术的长期通畅
DOI：
10.1097/sap.0000000000001674
复制
发表时间：
2019
影响因子：
1.5
通讯作者：
D. Ulrich
中科院分区：
文献类型：
--
作者：
H. Winters;H. Tielemans;A. Verhulst;V. Paulus;N. Slater;D. Ulrich
背景和目的淋巴水肿是一种严重影响患者生活质量的疾病。血管-静脉吻合术（LVA）在治疗水肿方面有良好的效果。目前尚不清楚在较长时间的随访后，股骨柄保持功能的比率。本研究的目的是确定1年随访时的LVA通畅性。方法回顾性分析2010年12月至2011年12月行左室心尖部瘤切除术患者的病历资料。在LVA后12个月随访时进行吲哚菁绿色淋巴造影的患者纳入本研究。在手术前以及6个月和12个月随访时进行体积测量。在术前和6个月随访时测量患者的生活质量。结果12例患者符合入选标准。总共有15/23例（56.5%）左心室动脉瘤被视为通畅。在8例患者（66.7%）中，至少有1例LVA可见。健康和患病手臂之间的体积差平均下降32.3%。生活质量平均提高1.4分。结论本研究首次评价了上肢水肿患者左室流出道的长期通畅性。我们的研究表明，至少56.5%的糖尿病患者在1年随访后是通畅的。
Background and Objectives Lymphedema is a condition that can greatly affect patient's quality of life. Promising results have been described with lymphaticovenular anastomosis (LVA) in the treatment of lymphedema. It is currently unknown at what rate anastomoses remain functional after a longer follow-up. The aim of this study was to determine LVA patency at 1-year follow-up. Methods Retrospective chart review was performed on patients who underwent LVA surgery. Patients who had indocyanine green lymphography performed at 12 months' follow-up after LVA were included in this study. Volume measurements were performed prior to surgery and at 6 and 12 months' follow-up. Patients quality of life was measured prior to surgery and at 6 months' follow-up. Results Twelve patients met inclusion criteria. In total, 15 (56.5%) of 23 LVAs were considered patent. In 8 patients (66.7%), at least 1 patent LVA was visible. The volume difference between the healthy and affected arms decreased 32.3% on average. Quality of life increased with 1.4 points on average. Conclusions This study is, to our knowledge, the first to evaluate long-term patency of LVA in upper limb lymphedema. Our study demonstrates that at least 56.5% of the anastomoses created are patent after 1-year follow-up.