Management of type 2 diabetes in geriatric patients.
Management of type 2 diabetes in geriatric patients.
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DOI：
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发表时间：
2010-09
影响因子：
3.4
通讯作者：
A. Rauseo;A. Pacilli;A. Palena;S. De Cosmo
中科院分区：
文献类型：
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作者：
A. Rauseo;A. Pacilli;A. Palena;S. De Cosmo
国际糖尿病联合会（IDF）指出，年龄在45岁以上是糖尿病的一个主要危险因素，并预测目前为1.9亿的糖尿病患者人数到2025年将翻一番。最近的几项试验表明，更严格的血糖控制可以减少糖尿病患者的长期并发症；然而，老年人严格控制血糖的结果尚不清楚。然而，老年人2型糖尿病的管理原则与中年人没有什么不同。有几个原因使血糖控制在目标范围内，对老年人也是如此；然而，应该考虑到低血糖的风险在老年人中更有害，应该避免。本综述将讨论旧的和最近的口服降糖药，以及较新的胰岛素类型。
The International Diabetes Federation (IDF) indicates age above 45 years as a major risk factor for diabetes and predicts that the number of persons with the disease, which currently stands at 190 million, will double by the year 2025. Several recent trials suggest that tighter glucose control reduces long-term complications in diabetic patients; however, outcomes of tight blood sugar control in the elderly are not known. Nevertheless, the principles of management of type 2 diabetes in the elderly are not different from those in middle-aged patients. There are several reasons to keep glucose control on target, also in the elderly; nonetheless, it should be considered that the risk of hypoglycemia is more deleterious in the elderly and should be avoided. The old and more recent oral glucose-lowering agents, along with the newer types of insulin, will be discussed in this review.