Wavefront-optimized ablation profiles:: Theoretical background
Wavefront-optimized ablation profiles:: Theoretical background
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DOI：
10.1016/j.jcrs.2004.01.026
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发表时间：
2004-04-01
影响因子：
2.8
通讯作者：
Löffler, J
中科院分区：
文献类型：
--
作者：
Mrochen, M;Donitzky, C;Löffler, J
目的：描述一种用于计算波前优化消融轮廓的方法，以预补偿近视、远视和屈光性角膜激光矫正引起的球面像差和高阶散光。设置：IROC-Institut fur Refraktive und Ophthalmo-Chirurgie和瑞士苏黎世联邦理工学院生物医学工程研究所。方法：近视、远视和屈光矫正的基本切削轮廓来自波前像差的二阶泽尼克表示。在烧蚀轮廓的理论计算中包括4阶球面像差和高阶散光允许对高阶像差（HOA）的预期量进行预补偿。波前优化的烧蚀轮廓的形状进行了比较与“经典”的烧蚀轮廓的形状近视和屈光correction.Results：引入预补偿球面像差和高阶散光导致一个更非球面的烧蚀轮廓与烧蚀深度的显着增加（高达35%）中周边的光学区。中心消融深度保持不变，在近视矫正，但增加了3%，在圆柱correction.Conclusions：波前优化的消融配置文件提供了一种简单的方法来预补偿预期的第四阶球面像差和高阶散光的平均眼睛。必须进行进一步的临床研究来证明理论结果;证明HOA的降低;并预测波前优化消融剖面的安全性、可预测性和稳定性。
Purpose: To describe a method for calculating wavefront-optimized ablation profiles to precompensate for the spherical aberration and higher-order astigmatism induced by myopic, hyperopic, and astigmatic corneal laser corrections.Setting: IROC-Institut fur Refraktive und Ophthalmo-Chirurgie, and Institute for Biomedical Engineering, Swiss Federal Institute of Technology, Zurich, Switzerland.Methods: The basic ablation profile for myopic, hyperopic, and astigmatic correction is derived from the 2nd-order Zernike representation of wavefront aberrations. Including 4th-order spherical aberration and higher-order astigmatism in the theoretical calculation of the ablation profile allows precompensation for the expected amount of higher-order aberrations (HOAs). The shapes of wavefront-optimized ablation profiles are compared with the shapes of "classic" ablation profiles for myopic and astigmatic corrections.Results: The introduction of precompensating spherical aberration and higher-order astigmatism leads to a more aspheric ablation profile with a significant increase in ablation depth (up to 35%) in the midperiphery of the optical zone. The central ablation depth remains unchanged in the myopic correction but increases by 3% in cylinder correction.Conclusions: Wavefront-optimized ablation profiles provide a simple method to precompensate for the expected 4th-order spherical aberration and higher-order astigmatism in the average eye. Further clinical studies must be performed to prove the theoretical results; demonstrate the reduction in HOAs; and predict safety, predictability, and stability of wavefront-optimized ablation profiles.