Introduction to nanozymes.
Introduction to nanozymes.
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纳米酶简介。
DOI：
10.1039/d3tb90199h
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Liu S
中科院分区：
文献类型：
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作者：
Liu S
对于这个集合，超过70%的出版物是原始研究，涵盖从纳米酶设计和机制到其应用的主题（图1A）。大量的这些论文集中在检测和治疗，而环境保护也代表，符合这一新兴的应用。迄今为止，许多类型的纳米材料已被用于模拟酶。目前，金属，金属氧化物和金属有机框架（MOFs）是最重要的代表，而其他也是很好的候选者，包括金属络合物，聚合物，碳，单原子，层状双氢氧化物和肽（图1B）。显然，大多数研究都集中在氧化还原酶样活性上，范围从过氧化物酶、氧化酶、单加氧酶和过氧化氢酶到超氧化物歧化酶和ROS清除活性（图1C）。值得注意的是，水解酶样纳米酶和生物正交纳米酶也已被几个小组研究。超过10篇评论（包括观点和小评论）包含在该集合中。它们涵盖了设计，检测，治疗和环境保护的主题（图1D）。功能范围
For this collection more than 70% of the publications are original studies, covering topics from nanozyme design and mechanisms to their applications (Fig. 1A). A large number of these papers are focused on detection and therapy, while environmental protection is also represented, consistent with this emerging application. To date, numerous types of nanomaterials have been exploited to mimic enzymes. Currently, metals, metal oxides, and metal–organic frameworks (MOFs) are most heavily represented, while others are also good candidates, including metal complexes, polymers, carbon, single atoms, layered double hydroxides, and peptides (Fig. 1B). Clearly, most of the studies are focused on oxidoreductaselike activities, ranging from peroxidase, oxidase, monooxygenase, and catalase to superoxide dismutase and ROS scavenging activities (Fig. 1C). Notably, hydrolase-like nanozymes and bioorthogonal nanozymes have also been investigated by several groups. Over ten reviews (including perspectives and minireviews) are included in the collection. They cover the topics of design, detection, therapy, and environmental protection (Fig. 1D). The range of functionalities