The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize
The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize
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DOI：
10.1016/j.molp.2019.02.009
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发表时间：
2019-03-04
期刊：
影响因子：
27.5
通讯作者：
Zhao, Jiuran
中科院分区：
文献类型：
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作者：
Li, Chunhui;Song, Wei;Zhao, Jiuran
玉米是一种全球重要的作物，也是遗传研究的经典模式植物。在这里，我们报告了一个2.2 Gb的基因组草图玉米品系，黄早四（HZS）。在中国，60%以上的玉米田都种植着由HILs培育的杂交种。6个完整的玉米基因组测序的蛋白质组聚类显示，638个蛋白质属于264个障碍特异性基因家族，其中大部分来自串联重复事件。通过对40个HILs相关系的重测序和比较分析，揭示了HILs的育种历史。60%以上的选择标记聚集在同一性遗传保守区域，产量相关基因/QTL富集在HZS特征选择区域。此外，我们证明了HESIS特异性家族基因在基因组中的分布并不均匀，而是在与改善/功能相关的基因组区域中富集。本研究为玉米基因组研究提供了重要的新资源，并扩大了我们对玉米基因组变异和改良历史的认识。
Maize is a globally important crop that was a classic model plant for genetic studies. Here, we report a 2.2 Gb draft genome sequence of an elite maize line, HuangZaoSi (HZS). Hybrids bred from HZS-improved lines (HILs) are planted in more than 60% of maize fields in China. Proteome clustering of six completed sequenced maize genomes show that 638 proteins fall into 264 HZS-specific gene families with the majority of contributions from tandem duplication events. Resequencing and comparative analysis of 40 HZS-related lines reveals the breeding history of HILs. More than 60% of identified selective sweeps were clustered in identity-by-descent conserved regions, and yield-related genes/QTLs were enriched in HZS characteristic selected regions. Furthermore, we demonstrated that HZS-specific family genes were not uniformly distributed in the genome but enriched in improvement/function-related genomic regions. This study provides an important and novel resource for maize genome research and expands our knowledge on the breadth of genomic variation and improvement history of maize.