The interstitial cystitis symptom index and problem index
The interstitial cystitis symptom index and problem index
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DOI：
10.1016/s0090-4295(99)80333-1
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发表时间：
1997-05-01
期刊：
影响因子：
2.1
通讯作者：
SpolarichKroll, J
中科院分区：
文献类型：
--
作者：
OLeary, MP;Sant, GR;SpolarichKroll, J
目标。目的：建立两种简单的自我给药指标，用于测量间质性膀胱炎（IC）患者的下尿路症状及其影响。在焦点小组中制定并评估了一套最初的问题。对3家有间质性膀胱炎经验的大型泌尿外科诊所（N=45）诊断的患者进行了修订、缩短和验证。对照组从妇科诊所的一组健康志愿者中招募（N=67）。评估了内部一致性、结构效度和重测信度。IC症状指数和IC问题指数测量尿和疼痛症状，并评估间质性膀胱炎患者的问题症状。两种仪器的心理测量性能都很好，症状指数表现出很好的区分患者和对照组特征的能力。这两个指标在IC患者的评估和管理中应该是有用的，尤其在针对这种疾病的新疗法的临床试验中应该是有用的，在这些试验中，可靠、有效和可重复的结果测量是至关重要的。(C) 1997年由爱思唯尔科学公司
Objectives. To develop 2 brief self-administered indices for measuring lower urinary tract symptoms and their impact in patients with interstitial cystitis (IC).Methods. An initial set of questions was developed and evaluated in focus groups. The index was revised, shortened, and validated with patients diagnosed in 3 large urologic practices with experience in interstitial cystitis (N=45). Controls were recruited from a group of healthy volunteers in a gynecology clinic (N=67). Internal consistency, construct validity, and test-retest reliability were evaluated.Results. The IC symptom index and the IC problem index measure urinary and pain symptoms and assesses how problematic symptoms are for patients with interstitial cystitis. Psychometric performance of both instruments is good, with the symptom index demonstrating excellent ability to discriminate characteristics between patients and controls.Conclusion. Both indices should be useful in the evaluation and management of patients with IC and should be particularly useful in clinical trials of new therapies for this condition, where reliable, validated, and reproducible outcome measures are critically important. (C) 1997 by Elsevier Science Inc.