Stannous chloride in alcohol: a one-pot conversion of 2-nitro-N-arylbenzamides to 2,3-dihydro-1H-quinazoline-4-ones.
Stannous chloride in alcohol: a one-pot conversion of 2-nitro-N-arylbenzamides to 2,3-dihydro-1H-quinazoline-4-ones.
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DOI：
10.1021/jo050450f
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发表时间：
2005-07
期刊：
影响因子：
--
通讯作者：
C. Yoo;J. Fettinger;M. Kurth
中科院分区：
文献类型：
--
作者：
C. Yoo;J. Fettinger;M. Kurth
以2-硝基苯甲酰胺为起始原料，经一步反应合成了2，3-二氢-1H-喹唑啉-4-酮。这些反应是由氯化亚锡在0.02 M的甲醇或乙醇盐酸溶液中介导的，并以良好的产率进行。
A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.