The structure of microtubule-motor complexes
The structure of microtubule-motor complexes
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DOI：
10.1016/s0955-0674(97)80145-7
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发表时间：
1997-02-01
影响因子：
7.5
通讯作者：
Hirose, K
中科院分区：
文献类型：
--
作者：
Amos, LA;Hirose, K
根据电子显微照片计算的新图像显示了微管和微管蛋白薄片的三维结构，这些微管和微管蛋白薄片按化学计量比装饰着球形马达蛋白结构域(Head)。动蛋白和NCD的单个头部以相同的方式结合到微管蛋白上的同一位置。NCD是与动蛋白反向移动的动蛋白相关蛋白。二聚体激动素和二聚体点头在第二个头部的位置上显示出有趣的不同。
New images, calculated from electron micrographs, show the three-dimensional structures of microtubules and tubulin sheets decorated stoichiometrically with globular motor protein domains (heads). Single heads of kinesin and ncd, the kinesin-related protein that moves in the reverse direction to kinesin, bind in the same way to the same site on tubulin. Dimeric kinesin and dimeric nod show an interesting difference in the positions of their second heads.