Rehabilitation with poststroke motor recovery: a review with a focus on neural plasticity.
Rehabilitation with poststroke motor recovery: a review with a focus on neural plasticity.
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中风后运动恢复的康复：重点关注神经可塑性的综述。
DOI：
10.1155/2013/128641
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发表时间：
2013
影响因子：
1.5
通讯作者：
Izumi S
中科院分区：
文献类型：
--
作者：
Takeuchi N;Izumi S
脑卒中后的运动恢复与神经可塑性有关，这涉及到新的神经元相互连接的发展、新功能的获得以及对损伤的补偿。然而，受中风影响的大脑半球的神经可塑性受损。因此，运动恢复疗法促进神经可塑性以补偿功能损失是很重要的。中风康复计划应包括在丰富的环境中进行有意义的、重复的、强化的和特定任务的运动训练，以促进神经可塑性和运动恢复。基于神经可塑性的基础科学和临床研究，各种新颖的脑卒中运动康复技术得到了发展。然而，康复干预在脑卒中患者中的效果差异很大，因为运动恢复的机制是不同的。神经生理学和神经影像学研究已经发展到评估中风后有效康复干预运动恢复机制的异质性。在此，我们回顾了与神经可塑性相关的新型卒中康复技术，并讨论了个性化的策略，以确定合适的治疗目标，防止适应性不良的可塑性，并最大限度地提高卒中患者的功能增益。
Motor recovery after stroke is related to neural plasticity, which involves developing new neuronal interconnections, acquiring new functions, and compensating for impairment. However, neural plasticity is impaired in the stroke-affected hemisphere. Therefore, it is important that motor recovery therapies facilitate neural plasticity to compensate for functional loss. Stroke rehabilitation programs should include meaningful, repetitive, intensive, and task-specific movement training in an enriched environment to promote neural plasticity and motor recovery. Various novel stroke rehabilitation techniques for motor recovery have been developed based on basic science and clinical studies of neural plasticity. However, the effectiveness of rehabilitative interventions among patients with stroke varies widely because the mechanisms underlying motor recovery are heterogeneous. Neurophysiological and neuroimaging studies have been developed to evaluate the heterogeneity of mechanisms underlying motor recovery for effective rehabilitation interventions after stroke. Here, we review novel stroke rehabilitation techniques associated with neural plasticity and discuss individualized strategies to identify appropriate therapeutic goals, prevent maladaptive plasticity, and maximize functional gain in patients with stroke.