Routine screening for intrauterine growth retardation in Germany: low sensitivity and questionable benefit for diagnosed cases
Routine screening for intrauterine growth retardation in Germany: low sensitivity and questionable benefit for diagnosed cases
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DOI：
10.1034/j.1600-0412.1998.770611.x
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发表时间：
1998-07-01
影响因子：
4.3
通讯作者：
Berle, P
中科院分区：
文献类型：
--
作者：
Jahn, A;Razum, O;Berle, P
背景胎儿生长迟缓的产前筛查已被证明在研究条件下检测高危妊娠是有效的。它也被广泛认为可以改善怀孕结果。我们评估了德国常规服务条件下胎儿宫内生长迟缓产前筛查常规的敏感性。然后，我们比较了小于胎龄儿产前诊断为生长迟缓与生长迟缓未被发现的新生儿的妊娠管理和结局。一项历史前瞻性研究，涵盖了德国一家三级妇产医院一年内分娩的所有2378例有产前记录的单胎妊娠。分娩记录与妊娠结局数据相关。基于超声和非系统性随访调查的常规筛查的灵敏度为32%，而在研究条件下报告的超声筛查的灵敏度为80-90%。产前诊断胎儿宫内发育迟缓与早产率高5倍有关（P
Background. Antenatal screening for fetal growth retardation has proven effective in detecting at-risk pregnancies under study conditions. It is also widely believed to improve pregnancy outcomes. We assessed sensitivity of antenatal screening routines for intrauterine growth retardation under routine service conditions in Germany. We then compared pregnancy management and outcome in small for gestational age neonates with antenatally diagnosed growth retardation to neonates whose growth retardation had remained undetected.Methods. Historical prospective study covering all 2378 singleton pregnancies with antenatal records delivered within a one-year period at a tertiary level maternity hospital in Germany. Antenatal records were linked with pregnancy outcome data.Results. The sensitivity of screening routines based on ultrasound and non-systematic followup investigations was 32% as compared to 80-90% reported for ultrasound screening under study conditions. An antenatal diagnosis of intrauterine growth retardation was associated with a 5 times higher rate of preterm delivery (p