Electron paramagnetic resonance (EPR) biodosimetry
Electron paramagnetic resonance (EPR) biodosimetry
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DOI：
10.1016/s0168-583x(01)00614-0
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发表时间：
2001-09-01
影响因子：
1.3
通讯作者：
Schauer, DA
中科院分区：
文献类型：
--
作者：
Desrosiers, M;Schauer, DA
辐射诱导电子顺磁共振(EPR)信号首先由Gordy等人报道。[程序。钉子。阿卡德。SCI。美国41(1955)983]。电子顺磁共振光谱在电离辐射剂量测量中的应用后来由Brady等人提出。[健康体检。15(1968)43]。从那时起，EPR剂量学被应用于事故和流行病学剂量重建、放射治疗。食品辐照、质量保证计划和考古年代测定。已被研究的材料包括骨、牙釉质、丙氨酸和石英。本文介绍了EPR生物剂量学的基本原理和应用。关于样品采集和准备的详细信息。EPR测量，剂量重建。并将回顾牙釉质的数据分析和解释。还将介绍EPR生物剂量学在意外过度暴露、放射性药物剂量评估和回溯性流行病学研究中的应用实例。(C)2001 Elsevier Science B.V.保留所有权利。
Radiation-induced electron paramagnetic resonance (EPR) signals were first reported by Gordy et al. [Proc. Nail. Acad. Sci. USA 41 (1955) 983]. The application of EPR spectroscopy to ionizing radiation dosimetry was later proposed by Brady et al. [Health Phys. 15 (1968) 43]. Since that time EPR dosimetry has been applied to accident and epidemiologic dose reconstruction, radiation therapy. food irradiation, quality assurance programs and archaeological dating. Materials that have been studied include bone, tooth enamel, alanine and quartz. This review paper presents the fundamentals and applications of EPR biodosimetry. Detailed information regarding sample collection and preparation. EPR measurements, dose reconstruction. and data analysis and interpretation will be reviewed for tooth enamel. Examples of EPR biodosimetry application in accidental overexposures, radiopharmaceutical dose assessment and retrospective epidemiologic studies will also be presented. (C) 2001 Elsevier Science B.V. All rights reserved.