The effects of spectacle wear in infancy on eye growth and refractive error in the marmoset (Callithrix jacchus)
The effects of spectacle wear in infancy on eye growth and refractive error in the marmoset (Callithrix jacchus)
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DOI：
10.1016/s0042-6989(98)00189-8
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发表时间：
1999-01-01
期刊：
影响因子：
1.8
通讯作者：
Judge, SJ
中科院分区：
文献类型：
--
作者：
Graham, B;Judge, SJ
我们对45只4-8周龄的绒猴进行了全面的研究，观察了戴眼镜对眼生长和屈光的影响。这一时期是在生命早期的时期，此时眼睛快速生长，屈光从远视变为其成人中度近视值。在一系列的实验中，我们研究了功率-8，-4，+4和+8D适合单眼的透镜的效果。在另一系列的实验中，我们研究了双眼配戴屈光力相等和相反的镜片的效果，其中双眼交替地被遮挡，以便激励使用双眼，特别是每天至少有一部分时间通过负透镜进行调节。佩戴-4D或-8D负透镜的眼睛的玻璃体腔，结合交替咬合，比对侧眼睛的玻璃体腔更快地伸长（负透镜眼睛-正透镜眼睛，0.21 +/- 0.03 mm（S.E.M.），P < 0.01和0.25 ± 0.06 mm，P < 0.05），并且变得相对更近视（分别为2.8 ± 0.26 D，P < 0.01和2.4 ± 0.61 D，P < 0.05）。戴-4D眼镜的眼睛单眼更迅速地伸长，变得比其他眼睛近视。戴+ 4D或+ XD镜片的眼睛受到的影响较小：单眼戴+ go镜片的动物（无交替遮挡）出现轻微的相对远视（0.99 +/- 0.21D，P
We made a comprehensive study, involving observations on 45 marmosets, of the effects on ocular growth and refraction of wearing spectacles from the ages of 4-8 weeks. This period was within the period early in life when the eye grows rapidly and refraction changes from hyperopia to its adult value of modest myopia. In one series of experiments we studied the effect of lenses of powers - 8, - 4, + 4 and + 8D fitted monocularly. In another series of experiments we studied the effect of lenses of equal and opposite powers fitted binocularly, with the two eyes alternately occluded, so as to give an incentive to use both eyes, and in particular to accommodate, for at least part of each day, through the negative lens. The vitreous chamber of eyes that wore negative lenses of - 4D or - 8D, combined with alternate occlusion, elongated more rapidly than that of the fellow eye (negative lens eye-positive lens eye, 0.21 +/- 0.03 mm (S.E.M.), P < 0.01 and 0.25 +/- 0.06 mm, P < 0.05, respectively) and became relatively more myopic (2.8 +/- 0.26D, P < 0.01 and 2.4 +/- 0.61D, P < 0.05 respectively). Eyes that wore - 4D lenses monocularly elongated more rapidly and became myopic than fellow eyes. Eyes that wore + 4D or + XD lenses were less strongly affected: animals that wore + go lenses monocularly (without alternate occlusion) developed a slight relative hyperopia (0.99 +/- 0.21D, P