Distraction and Placebo: Two Separate Routes to Pain Control
Distraction and Placebo: Two Separate Routes to Pain Control
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DOI：
10.1177/0956797611427919
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发表时间：
2012-03-01
影响因子：
8.2
通讯作者：
Wager, Tor D.
中科院分区：
文献类型：
--
作者：
Buhle, Jason T.;Stevens, Bradford L.;Wager, Tor D.
最近的研究爆炸性地研究了安慰剂治疗是否会影响与健康相关的结果及其生物标志物，但几乎没有研究研究过安慰剂效应发生所需的心理过程。这项研究测试了安慰剂治疗和认知分散是否通过共享或独立的过程减少疼痛。我们测试了执行工作记忆任务和安慰剂治疗对热痛感知的联合影响。这两种操作的交互作用将构成共享机制的证据，而累加效应将意味着单独的机制。参与者（N = 33）报告说，当他们进行工作记忆任务时，当他们接受安慰剂治疗时，疼痛减轻，但减少是累加的，结果表明，工作记忆任务的执行要求不干扰安慰剂镇痛。此外，安慰剂镇痛并不损害任务的表现。总之，这些数据表明，安慰剂镇痛并不依赖于主动重定向的注意力和期望和分心可以结合起来，以最大限度地缓解疼痛。
An explosion of recent research has studied whether placebo treatments influence health-related outcomes and their biological markers, but almost no research has examined the psychological processes required for placebo effects to occur. This study tested whether placebo treatment and cognitive distraction reduce pain through shared or independent processes. We tested the joint effects of performance of an executive working memory task and placebo treatment on thermal pain perception. An interactive effect of these two manipulations would constitute evidence for shared mechanisms, whereas additive effects would imply separate mechanisms. Participants (N = 33) reported reduced pain both when they performed the working memory task and when they received the placebo treatment, but the reductions were additive, a result indicating that the executive demands of the working memory task did not interfere with placebo analgesia. Furthermore, placebo analgesia did not impair task performance. Together, these data suggest that placebo analgesia does not depend on active redirection of attention and that expectancy and distraction can be combined to maximize pain relief.