Comparison and analysis of inter-subject variability of simulated magnetic activity generated from gastric electrical activity

Comparison and analysis of inter-subject variability of simulated magnetic activity generated from gastric electrical activity
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DOI:
10.1007/s10439-008-9480-5
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发表时间:
2008-06-01
影响因子:
3.8
通讯作者:
Pullan, Andrew J.
Pullan, Andrew J.
中科院分区:
工程技术2区
文献类型:
--
作者:
Komuro, Rie;Cheng, Leo K.;Pullan, Andrew J.

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由胃电活动(GEA)产生的胃电图(EGG)用作非侵入性方法以帮助评估受试者的胃部状况。据记载,GEA产生的磁活动记录更可靠。通常,通过GEA的磁性测量,仅记录垂直于身体的活动。此外,外部解剖标志用于将磁记录设备SQUID(超导量子干涉设备)定位在胃上,而不考虑体型。在这里介绍的工作中,GEA及其相应的磁活动进行了模拟。使用这些数据,我们调查使用标准的SQUID位置以及定制的SQUID位置的影响和垂直于身体的磁分量对磁场的贡献。我们还探讨了胃壁厚度对合成磁场的影响。模拟结果表明,壁厚越厚,保持相同信号模式的磁场强度越大。我们的结论是,大部分的磁活动所产生的GEA发生在一个平面平行于前体。我们还得出结论,使用标准的SQUID位置可能是次优的。
Electrogastrograms (EGGs) produced from gastric electrical activity (GEA) are used as a non-invasive method to aid in the assessment of a subject's gastric condition. It has been documented that recordings of the magnetic activity generated from GEA are more reliable. Typically, with magnetic measurements of GEA, only activity perpendicular to the body is recorded. Also, external anatomical landmarks are used to position the magnetic recording devices, SQUIDs, (Superconducting Quantum Interference Devices) over the stomach with no allowance made for body habitus. In the work presented here, GEA and its corresponding magnetic activity are simulated. Using these data, we investigate the effects of using a standard SQUID location as well as a customized SQUID position and the contribution the magnetic component perpendicular to the body makes to the magnetic field. We also explore the effects of the stomach wall thickness on the resultant magnetic fields. The simulated results show that the thicker the wall, the larger the magnitude of the magnetic field holding the same signal patterns. We conclude that most of the magnetic activity arising from GEA occurs in a plane parallel to the anterior body. We also conclude that using a standard SQUID position can be suboptimal.