Block-copolymer-assisted synthesis of hydroxyapatite nanoparticles with high surface area and uniform size
Block-copolymer-assisted synthesis of hydroxyapatite nanoparticles with high surface area and uniform size
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DOI：
10.1088/1468-6996/12/4/045005
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发表时间：
2011-08-01
影响因子：
5.5
通讯作者：
Yamauchi, Yusuke
中科院分区：
文献类型：
--
作者：
Huang, Yu-Tzu;Imura, Masataka;Yamauchi, Yusuke
我们报告的羟基磷灰石纳米粒子（HANPs）的合成共沉淀法使用D-葡萄糖酸钙和磷酸氢钾作为钙和磷酸根离子的来源，分别，和三嵌段共聚物F127作为稳定剂。使用扫描电子显微镜，X-射线衍射和氮吸附/脱附等温线的HANPs进行了表征。通过溶剂萃取或煅烧除去F127改变了HANPs的结构。溶剂萃取的HANPs是单晶，其< 001 >轴沿HANPs的棒轴沿着取向，而煅烧的HANPs包含两个晶相，导致球形形态。煅烧后的HANPs比表面积（127 m2·g-1）远高于溶剂萃取后的HANPs（44 m2·g-1）。
We report the synthesis of hydroxyapatite nanoparticles (HANPs) by the coprecipitation method using calcium D-gluconate and potassium hydrogen phosphate as the sources of calcium and phosphate ions, respectively, and the triblock copolymer F127 as a stabilizer. The HANPs were characterized using scanning electron microscopy, x-ray diffraction, and nitrogen adsorption/desorption isotherms. Removal of F127 by solvent extraction or calcination alters the structure of HANPs. The solvent-extracted HANPs were single crystals with their < 001 > axis oriented along the rod axis of the HANP, whereas the calcined HANPs contained two crystal phases that resulted in a spherical morphology. The calcined HANPs had much higher surface area (127m(2) g(-1)) than the solvent-extracted HANPs (44m(2) g(-1)).