Stereoselective synthesis of three-membered ring compounds via ylide routes
Stereoselective synthesis of three-membered ring compounds via ylide routes
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DOI：
10.1351/pac199971030369
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发表时间：
1999-03-01
影响因子：
1.8
通讯作者：
Zhou, YG
中科院分区：
文献类型：
--
作者：
Dai, LX;Hou, XL;Zhou, YG
通过叶立德路线可以立体选择性地合成三种类型的小环化合物（环氧化物、氮丙啶和环丙烷）。其中，乙烯基环氧乙烷、乙烯基氮丙啶、环丙酯、酰胺和酮的立体化学可以通过选择反应条件和具有不同杂原子和配体的叶立德来调节。光学活性环氧化物和乙炔基氮丙啶可以通过樟脑衍生的手性锍叶立德路线制备。
Three types of small ring compounds (epoxides, aziridines and cyclopropanes) can be synthesized stereoselectively via ylide route. Among them, the stereochemistry of vinyloxiranes, vinylaziridines, cyclopropylesters, amides and ketones can be tuned by the choice of reaction conditions and ylides with varying heteroatoms and ligands. Optically active epoxides and acetylenylaziridines can be prepared via camphor-derived chiral sulfonium ylide routes.