[Etiologic factors and incidence of ischemic type biliary lesions (ITBL) after liver transplantation].
[Etiologic factors and incidence of ischemic type biliary lesions (ITBL) after liver transplantation].
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发表时间：
1998
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通讯作者：
J. Langrehr;A. Schneller;R. Neuhaus;Thomas Vogl;R. Hintze;Peter Neuhaus
中科院分区：
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作者：
J. Langrehr;A. Schneller;R. Neuhaus;Thomas Vogl;R. Hintze;Peter Neuhaus
缺血型胆管病变（ITBL）被定义为肝移植后移植物胆管树的非缺血性和非免疫性破坏。在回顾性分析中，我们调查了可能的病因和 ITBL 的发病率。与之前的研究不同，ITBL的发生率较低（2.6%），并且我们没有观察到冷缺血时间或初始转氨酶峰值作为再灌注损伤指标的显着影响。然而，我们发现自取器官和动脉压灌注保存的器官中 ITBL 的发生率显着降低。
Ischemic type biliary lesions (ITBL) are defined as non-ischemic and non-immunological destruction of the graft's biliary tree after liver transplantation. In a retrospective analysis we investigated possible etiological factors and the incidence of ITBL. Differing from previous studies, the incidence of ITBL was low (2.6%) and we did not observe a significant effect of cold ischemic time or initial peak transaminases, as indicator of the reperfusion injury. However, we detected a significant decrease in the incidence of ITBL in self-retrieved organs and in organs preserved with arterial pressure perfusion.