Hepatobiliary Tumors: Update on Diagnosis and Management.
Hepatobiliary Tumors: Update on Diagnosis and Management.
复制标题
DOI：
10.14218/jcth.2015.00012
复制
发表时间：
2015-09-28
影响因子：
3.6
通讯作者：
Tadros M
中科院分区：
文献类型：
--
作者：
Kabbach G;Assi HA;Bolotin G;Schuster M;Lee HJ;Tadros M
肝脏和胆道肿瘤，主要是肝细胞癌和胆管癌，是全世界癌症相关死亡的第二大原因，也是发达国家男性癌症相关死亡的第六大原因。生物标志物和成像方式的最新发展增强了这些高度致命的恶性肿瘤的早期检测和准确诊断。这些进步包括血清学检测、微核糖核酸、荧光原位杂交、超声造影和肝胆相磁共振成像。此外，这些肿瘤的手术和非手术治疗也取得了重大进展，包括扩大肝移植标准、新的局部治疗和分子靶向治疗。在本文中，我们回顾了各种类型的肝胆肿瘤，并讨论了其诊断和治疗的新进展。
Tumors of the liver and biliary tree, mainly hepatocellular carcinoma and cholangiocarcinoma, are the second leading cause of cancer related death worldwide and the sixth leading cause of cancer related death among men in developed countries. Recent developments in biomarkers and imaging modalities have enhanced early detection and accurate diagnosis of these highly fatal malignancies. These advances include serological testing, micro-ribonucleic acids, fluorescence in situ hybridization, contrast-enhanced ultrasound, and hepatobiliary-phase magnetic resonance imaging. In addition, there have been major developments in the surgical and nonsurgical management of these tumors, including expansion of the liver transplantation criteria, new locoregional treatments, and molecularly targeted therapies. In this article, we review various types of hepatobiliary tumors and discuss new developments in their diagnosis and management.