The immunology of scabies.
The immunology of scabies.
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疥疮的免疫学。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
Dahl Mv
中科院分区：
文献类型：
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作者：
R. Cabrera;A. Agar;Dahl Mv
溃疡病患者对叮咬的反应是在叮咬部位产生细胞介导的免疫反应。这会引起一个非常痒的丘疹，通常会被磨掉。有时，皮肤中的其他免疫反应会导致溃烂丘疹、血管炎和结节。免疫球蛋白G(Ig G)、Ig M，尤其是Ig E类抗体介导的免疫反应也可能参与。所有这些反应都没有被证明可以消除皮肤表面的所有螨虫，但在局部，这些反应可能会防止皮肤表面溃烂的微生物的流行繁殖，就像在一些结痂的溃烂患者中观察到的那样。
Individuals with scabies react to bites by generating a cell-mediated immune response at the bite site. This elicits a very itchy papule that is often excoriated. Sometimes ulcerated papules, vasculitis, and nodules develop as a result of other immunologic reactions in skin. Immunologic reactions mediated by antibodies of the immunoglobulin G (IgG), IgM, and especially, IgE classes may also be involved. None of these reactions have been shown to eliminate all mites from the skin surface, but locally these reactions may prevent the epidemic multiplication of scabies' organisms on the skin surface, as observed in some patients with crusted scabies.