Total complement activity in maternal sera, amniotic fluids and cord sera in women with premature labor, premature rupture of membranes or chorioamnionitis.
Total complement activity in maternal sera, amniotic fluids and cord sera in women with premature labor, premature rupture of membranes or chorioamnionitis.
复制标题
早产、胎膜早破或绒毛膜羊膜炎妇女的母体血清、羊水和脐带血清中的总补体活性。
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
W. Ledger
中科院分区：
文献类型：
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作者：
J. Huffaker;S. Witkin;L. Cutler;M. Druzin;W. Ledger
对119例妊娠24~40周的早产宫缩、胎膜早破、绒毛膜羊膜炎或ALL孕妇的母血、羊水、脐血或ALL进行了总溶血补体活性(CH50)测定。孕妇血清的平均CH50超过羊水和脐带血清的平均CH50。羊水CH50平均值超过脐带血清，在32周时显著升高。这一上升先于脐带血清的平均CH50，后者发生在胎儿体重约2500克时。羊水CH50平均值与脐带血CH50呈显著负相关。这三种液体中的CH50水平没有区分早产和足月分娩的早产儿宫缩患者。胎膜早破患者的CH50与正常妊娠妇女的CH50没有差别。绒毛膜羊膜炎患者母体血清的平均CH50升高，但不能预测绒毛膜羊膜炎。在吸烟和静脉注射利托君的患者中，母亲血清的平均CH50降低。
Total hemolytic complement activity (CH50) was determined in maternal sera, amniotic fluids or cord sera, or all, from 119 patients with preterm uterine contractions, premature rupture of membranes or chorioamnionitis, or all, at 24 to 40 weeks of gestation. The mean CH50 of maternal sera exceeded the mean CH50 of both amniotic fluids and cord sera. The mean CH50 of amniotic fluids exceeded that of cord sera and increased significantly at 32 weeks. This rise preceded that of the mean CH50 of cord sera, which occurred at a fetal weight of approximately 2,500 grams. The mean CH50 of amniotic fluids varied significantly and inversely with that of cord sera. The levels of CH50 in these three fluids did not distinguish between patients with preterm uterine contractions who delivered prematurely and those who delivered at term. The CH50 in patients with premature rupture of membranes did not differ from a control population of women with uncomplicated pregnancies. The mean CH50 of maternal sera was increased in patients with chorioamnionitis but was not predictive of chorioamnionitis. The mean CH50 of maternal sera was decreased in patients who smoked cigarettes and in patients who received intravenous ritodrine.