Social status and susceptibility to respiratory infections

Social status and susceptibility to respiratory infections
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DOI:
10.1111/j.1749-6632.1999.tb08119.x
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发表时间:
1999-01-01
期刊:
SOCIOECONOMIC STATUS AND HEALTH IN INDUSTRIAL NATIONS
影响因子:
--
通讯作者:
Cohen, S
Cohen, S
中科院分区:
其他
文献类型:
--
作者:
Cohen, S

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社会经济地位较低的成年人和儿童患各种传染病的风险较高,特别是呼吸道感染。SES较低的人感染性疾病的风险较高,这被认为是由于接触传染性病原体的增加和宿主对感染的抵抗力下降。我们总结了三项研究,研究了几个社会地位的标志物(失业,感知和观察的社会地位)与宿主对上呼吸道感染的抵抗力的前瞻性关联。失业与成年人感染的易感性增加有关。雄性猴子较低的社会地位也与易感性增加有关,人类较低的社会地位也是如此。社会地位和易感性的关联主要是由社会地位最低群体的风险增加来解释的。然而,在猴子和人类中,社会地位的进一步提高与易感性的进一步降低有关。
Adults and children of lower socioeconomic status (SES) are at higher risk for a wide range of communicable infectious diseases, especially respiratory infections. Greater risk for infectious illness among people with lower SES is thought to be attributable to increased exposure to infectious agents and decreased host resistance to infection. We summarize three studies that examine the prospective association of several markers of social status (unemployment, perceived and observed social status) with host resistance to upper respiratory infections. Unemployment was associated with increased susceptibility to infection in adult humans. Lower social status in male monkeys was also associated with increased susceptibility, as was lower perceived social status in humans. The association of social status and susceptibility was accounted for primarily by increased risk in the lowest social status groups. However, further increases in social status were associated with further decreases in susceptibility in both monkeys and humans.