Remarkable response of lipoid proteinosis to oral dimethyl sulphoxide
Remarkable response of lipoid proteinosis to oral dimethyl sulphoxide
复制标题
类脂蛋白沉积症对口服二甲亚砜有显着反应
DOI：
10.1111/j.1365-2133.1988.tb03260.x
复制
发表时间：
1988
影响因子：
10.3
通讯作者：
Chrang
中科院分区：
文献类型：
--
作者：
Chu‐Kwan Wong;Chrang
我们报告了一名41岁男性使用口服二甲基亚砜成功治疗类脂质蛋白沉积症的病例。初始剂量为40 mg/kg/天，然后逐渐增加至60 mg/kg/天。经过3年的治疗，患者的皮肤病变、声音嘶哑和食管功能异常明显改善。除了患者呼吸中有大蒜样气味外，未观察到任何副作用。
We report the successful treatment of lipoid proteinosis in a 41‐year‐old man using oral dimethyl sulphoxide. The initial dosage was 40 mg/kg/day, which was then increased progressively to 60 mg/kg/day. After 3 years of treatment, the patient's skin lesions, hoarseness of voice and abnormal oesophageal function improved remarkably. No side‐effects were noted except for a garlic‐like smell on the patient's breath.