Highly active antiretroviral therapy associated with improved anemia among HIV-infected women.
Highly active antiretroviral therapy associated with improved anemia among HIV-infected women.
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高效抗逆转录病毒治疗与艾滋病毒感染女性贫血的改善相关。
DOI：
10.1089/108729101753145466
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
HER(HumanImmunodeficiencyVirusEpidemiologyResearch)StudyGroup
中科院分区：
文献类型：
--
作者：
Semba,RD;Shah,N;Klein,RS;Mayer,KH;Schuman,P;Gardner,LI;Vlahov,D;HER(HumanImmunodeficiencyVirusEpidemiologyResearch)StudyGroup
Anemia is common during human immunodeficiency virus (HIV) infection and is associated with increased mortality. We conducted a study to examine the impact of highly active antiretroviral therapy (HAART) on anemia in a multicenter cohort of HIV-positive women, the Human Immunodeficiency Virus Epidemiology Research (HER) Study. Among women receiving HAART (n= 188), non-HAART monotherapy or combination antiretroviral therapy (ART) (n= 111), or who had no reported treatment (n= 62), the prevalence of anemia (hemoglobin, <120 g/L) at baseline was 38.3, 36.9, and 43.6%, respectively (p= 0.58) and at 1-year follow-up was 26.1%, 36.9%, 45.2%, respectively (p= 0.01); mean hemoglobin at baseline was 125 ± 16, 122 ± 16, and 122 ± 18 g/L, respectively (p= 0.29) and at 1-year follow-up was 128 ± 14, 123 ± 16, and 119 ± 20 g/L, respectively (p< 0.0001). Adjusted linear regression models showed that HAART was associated with an increase of hemoglobin of 0.20 g/L per month (p= 0.007). After 1 year of treatment, HAART was associated with a 32% reduction in anemia among HIV-infected women (p= 0.01), whereas there was no significant change in the prevalence of anemia among those on non-HAART ART or those who had no reported treatment. HAART is associated with a large reduction in anemia among HIV-infected women.
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DOI：
10.1016/c2018-0-02533-5
发表时间：
1996
期刊：
--
影响因子：
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作者：
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影响因子：
6.5
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DOI：
10.1097/00042560-199904150-00006
发表时间：
1999
期刊：
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
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作者：
A. Rompalo;J. Astemborski;E. Schoenbaum;P. Schuman;C. Carpenter;S. Holmberg;D. Warren;H. Farzadegan;D. Vlahov;D. Smith
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DOI：
10.1016/s0889-8588(18)30438-6
发表时间：
1991
期刊：
Hematology/oncology clinics of North America
影响因子：
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作者：
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