Widespread activity of multiple lineages of Usutu virus, western Europe, 2016
Widespread activity of multiple lineages of Usutu virus, western Europe, 2016
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DOI：
10.2807/1560-7917.es.2017.22.4.30452
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发表时间：
2017-01-26
期刊：
影响因子：
19
通讯作者：
Schmidt-Chanasit, J.
中科院分区：
文献类型：
--
作者：
Cadar, D.;Luehken, R.;Schmidt-Chanasit, J.
2016年夏天，比利时、法国、德国和荷兰根据活禽和死禽监测报告了大范围的禽流感病毒活动。致病性USUV菌株代表四个谱系，其中两个推定的新谱系最有可能是最近引入德国并传播到其他西欧国家。R-O值> 1时，暴发区的空间范围对应。此次爆发是迄今为止在欧洲登记的最大的USUV动物流行病，使我们能够深入了解最近引入的具有潜在公共卫生影响的虫媒病毒如何在幼稚环境中传播并成为常驻病原体。了解推动USUV出现或重新出现的生态和流行病学因素对于制定和实施及时的监测战略以采取适当的预防和控制措施至关重要。发现USUV的国家的公共卫生当局、输血服务机构和临床医生应意识到人类可能感染USUV的风险，包括不明原因脑炎或其他神经损伤患者，特别是在夏末蚊子密度达到高峰时。
In the summer of 2016, Belgium, France, Germany and the Netherlands reported widespread Usutu virus (USUV) activity based on live and dead bird surveillance. The causative USUV strains represented four lineages, of which two putative novel lineages were most likely recently introduced into Germany and spread to other western European countries. The spatial extent of the outbreak area corresponded with R-O values > 1. The occurrence of the outbreak, the largest USUV epizootic registered so far in Europe, allowed us to gain insight in how a recently introduced arbovirus with potential public health implications can spread and become a resident pathogen in a naive environment. Understanding the ecological and epidemiological factors that drive the emergence or re-emergence of USUV is critical to develop and implement timely surveillance strategies for adequate preventive and control measures. Public health authorities, blood transfusion services and clinicians in countries where USUV was detected should be aware of the risk of possible USUV infection in humans, including in patients with unexplained encephalitis or other neurological impairments, especially during late summer when mosquito densities peak.