SENILE ATROPHY OF THE HUMAN LACRIMAL GLAND - THE CONTRIBUTION OF CHRONIC INFLAMMATORY DISEASE
SENILE ATROPHY OF THE HUMAN LACRIMAL GLAND - THE CONTRIBUTION OF CHRONIC INFLAMMATORY DISEASE
复制标题
DOI：
10.1136/bjo.68.9.674
复制
发表时间：
1984-01-01
影响因子：
4.1
通讯作者：
LEE, WR
中科院分区：
文献类型：
--
作者：
DAMATO, BE;ALLAN, D;LEE, WR
对99例人泪腺的组织学检查显示，分泌腺泡萎缩与分泌管阻塞、上升性导管周围纤维化和淋巴细胞性和多形性炎症引起的邻近血管闭塞之间存在关系。通过免疫组织化学对B淋巴细胞系列的亚组进行的研究未显示出随年龄、性别、纤维化或淋巴细胞炎症的任何统计学变化。老年性萎缩是泪腺衰老退化的结果，这一概念在组织学研究结果的基础上受到质疑。
Histological examination of 99 human lacrimal glands showed a relationship between atrophy of the secretory acini and secretory duct obstruction, ascending periductal fibrosis, and obliteration of the adjacent blood vessels caused by lymphocytic and polymorphonuclear inflammation. Investigation of the subgroups of the B lymphocytic series by immunohistochemistry did not show any statistical change with age, sex, fibrosis, or lymphocytic inflammation. The concept of senile atrophy occurring as a result of senescent involution of the lacrimal gland is challenged on the basis of the histological findings.