SYNOVIAL HISTOLOGY IN CARPAL-TUNNEL SYNDROME
SYNOVIAL HISTOLOGY IN CARPAL-TUNNEL SYNDROME
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DOI：
10.1016/0363-5023(91)90208-s
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发表时间：
1991-07-01
影响因子：
1.9
通讯作者：
MYERS, LD
中科院分区：
文献类型：
--
作者：
FUCHS, PC;NATHAN, PA;MYERS, LD
本研究探讨特发性腕管综合征和肌腱滑膜组织学，特别是炎症之间的关系。 从腕管松解患者中获得了177个手腕的肌腱滑液活检样本，还获得了对照组的19个样本。 炎症仅存在于10%的患者标本中，并且仅与所研究的临床和组织学因素之一相关，即，神经传导障碍 经常观察到的水肿（85%）与炎症无关。 血管硬化也被一致地发现（98%），并与患者的年龄和水肿程度相关。 水肿和血管硬化发生的频率和严重程度显着更大的标本中的患者比对照组。 纤维化（3%）和滑膜增生（1%）是不常见的发现。 因此，特发性腕管综合征手术治疗时，腱鞘炎并不常见。
This study investigates the relationship between idiopathic carpal tunnel syndrome and tenosynovial histology, specifically inflammation. Tenosynovial biopsy specimens from 177 wrists were obtained from patients at carpal tunnel release, and a control group of 19 specimens was also obtained. Inflammation was present in only 10% of the patient specimens and was correlated with only one of the clinical and histologic factors studied, i.e., nerve conduction impairment. Edema, observed freqeuently (85%), was not correlated with inflammation. Vascular sclerosis was also found consistently (98%) and was correlated with patient age and degree of edema. Edema and vascular sclerosis occurred with significantly greater frequency and severity in the specimens of patients than in the control group. Fibrosis (3%) and synovial hyperplasia (1%) were uncommon findings. It is concluded that tenosynovitis is uncommon in patients undergoing surgery for treatment of idiopathic carpal tunnel syndrome.