Short- and Long-Term MRI Assessed Hemodynamic Changes in Pediatric Moyamoya Patients After Revascularization.
Short- and Long-Term MRI Assessed Hemodynamic Changes in Pediatric Moyamoya Patients After Revascularization.
复制标题
DOI：
10.1002/jmri.28902
复制
发表时间：
2023-07
影响因子：
4.4
通讯作者：
Moss Y. Zhao;Elizabeth Tong;Rui Duarte Armindo;Ates Fettahoglu;Jason J. Choi;Jacob Bagley;K. Yeom;Mike E Moseley;G. Steinberg;G. Zaharchuk
中科院分区：
文献类型：
--
作者：
Moss Y. Zhao;Elizabeth Tong;Rui Duarte Armindo;Ates Fettahoglu;Jason J. Choi;Jacob Bagley;K. Yeom;Mike E Moseley;G. Steinberg;G. Zaharchuk
脑血管储备(CVR)反映了血管扩张挑战后脑血流量(CBF)的变化能力。脑血管疾病患者的CVR降低与较高的中风风险相关。尽管血管重建术可以改善成年血管病变患者(如烟雾病患者)的CVR并降低这种风险，但其对儿童患者血流动力学的影响仍有待阐明。动脉自旋标记(ASL)是一种定量MRI技术，可以无创地测量CBF、CVR和动脉通过时间(ATT)。
Cerebrovascular reserve (CVR) reflects the capacity of cerebral blood flow (CBF) to change following a vasodilation challenge. Decreased CVR is associated with a higher stroke risk in patients with cerebrovascular diseases. While revascularization can improve CVR and reduce this risk in adult patients with vasculopathy such as those with Moyamoya disease, its impact on hemodynamics in pediatric patients remains to be elucidated. Arterial spin labeling (ASL) is a quantitative MRI technique that can measure CBF, CVR, and arterial transit time (ATT) non‐invasively.