Collaborative computational project for electron cryo-microscopy.
Collaborative computational project for electron cryo-microscopy.
复制标题
DOI：
10.1107/s1399004714018070
复制
发表时间：
2015-01-01
期刊：
影响因子：
--
通讯作者：
Winn M
中科院分区：
文献类型：
--
作者：
Wood C;Burnley T;Patwardhan A;Scheres S;Topf M;Roseman A;Winn M
电子冷冻显微镜合作计算项目（CCP-EM）是继CCP 4在大分子晶体学方面取得成功之后，结构生物学社区的一项新举措。报告了在支持cryoEM软件的用户和开发人员方面取得的进展。电子冷冻显微镜合作计算项目（CCP-EM）最近成立。该项目的目标有三个方面：建立一个连贯的cryoEM社区，为科学家个人提供支持，并作为与其他社区联络的协调中心，支持实践科学家使用cryoEM软件，最后支持软件开发人员制作和传播强大且用户友好的程序。该项目以大分子晶体学的CCP 4为模型，正在开发共同感兴趣的领域，如模型拟合，基础软件库和构建程序包的工具。然而，cryoEM包括许多技术，涵盖了大范围的分辨率和一个独特的项目是必要的。在这篇文章中，迄今为止的进展报告和未来的计划进行了讨论。
The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) is a new initiative for the structural biology community, following the success of CCP4 for macromolecular crystallography. Progress in supporting the users and developers of cryoEM software is reported. The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) has recently been established. The aims of the project are threefold: to build a coherent cryoEM community which will provide support for individual scientists and will act as a focal point for liaising with other communities, to support practising scientists in their use of cryoEM software and finally to support software developers in producing and disseminating robust and user-friendly programs. The project is closely modelled on CCP4 for macromolecular crystallography, and areas of common interest such as model fitting, underlying software libraries and tools for building program packages are being exploited. Nevertheless, cryoEM includes a number of techniques covering a large range of resolutions and a distinct project is required. In this article, progress so far is reported and future plans are discussed.