Does cognitive behavioral therapy alter mental defeat and cognitive flexibility in patients with panic disorder?
Does cognitive behavioral therapy alter mental defeat and cognitive flexibility in patients with panic disorder?
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DOI：
10.1186/s13104-018-3130-2
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发表时间：
2018-01-12
影响因子：
1.8
通讯作者：
Shimizu E
中科院分区：
文献类型：
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作者：
Nagata S;Seki Y;Shibuya T;Yokoo M;Murata T;Hiramatsu Y;Yamada F;Ibuki H;Minamitani N;Yoshinaga N;Kusunoki M;Inada Y;Kawasoe N;Adachi S;Oshiro K;Matsuzawa D;Hirano Y;Yoshimura K;Nakazato M;Iyo M;Nakagawa A;Shimizu E
精神挫败和认知灵活性被作为抑郁症和创伤后应激障碍的解释因素进行了研究。这项研究检测了惊恐障碍(PD)患者在认知行为治疗(CBT)前后的精神挫败感和认知灵活性得分，并将它们与性别和年龄匹配的健康对照组进行了比较。帕金森病患者(n=15)每周接受16次CBT治疗，对照组(n=35)不接受任何治疗。患者在干预前、8次CBT治疗后和16次CBT治疗后完成了心理挫败量表和认知灵活性量表，而对照组只在接受CBT(基线)之前完成了这一任务。患者CBT前心理挫败量表和认知灵活性量表得分显著高于对照组，认知灵活性量表得分显著低于对照组。此外，患者的精神挫败量表平均分从22.2分下降到12.4分，而认知灵活性量表的平均分从42.8分增加到49.5分。这些结果表明，CBT可以减少PD试验注册患者的精神挫败感，增加认知灵活性。该研究于2016年6月10日在全国Umin临床试验注册中心进行了回顾性注册(注册ID：UMIN000022693)。本文的在线版本(10.1186/s13104-0183130-2)包含补充材料，可供授权用户使用。
Mental defeat and cognitive flexibility have been studied as explanatory factors for depression and posttraumatic stress disorder. This study examined mental defeat and cognitive flexibility scores in patients with panic disorder (PD) before and after cognitive behavioral therapy (CBT), and compared them to those of a gender- and age-matched healthy control group. Patients with PD (n = 15) received 16 weekly individual CBT sessions, and the control group (n = 35) received no treatment. Patients completed the Mental Defeat Scale and the Cognitive Flexibility Scale before the intervention, following eight CBT sessions, and following 16 CBT sessions, while the control group did so only prior to receiving CBT (baseline). The patients’ pre-CBT Mental Defeat and Cognitive Flexibility Scale scores were significantly higher on the Mental Defeat Scale and lower on the Cognitive Flexibility Scale than those of the control group participants were. In addition, the average Mental Defeat Scale scores of the patients decreased significantly, from 22.2 to 12.4, while their average Cognitive Flexibility Scale scores increased significantly, from 42.8 to 49.5. These results suggest that CBT can reduce mental defeat and increase cognitive flexibility in patients with PD Trial registration The study was registered retrospectively in the national UMIN Clinical Trials Registry on June 10, 2016 (registration ID: UMIN000022693). The online version of this article (10.1186/s13104-018-3130-2) contains supplementary material, which is available to authorized users.