An enzyme-free fluorescent probe based on carbon dots - MnO2 nanosheets for determination of uric acid
An enzyme-free fluorescent probe based on carbon dots - MnO2 nanosheets for determination of uric acid
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DOI：
10.1016/j.jphotochem.2018.02.002
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发表时间：
2018-04-01
影响因子：
4.3
通讯作者：
Kouhi, Zahra
中科院分区：
文献类型：
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作者：
Amjadi, Mohammad;Hallaj, Tooba;Kouhi, Zahra
报道了一种基于MnO 2纳米片对硫氮共掺杂碳点（S，N-CD）荧光的影响的开启型荧光探针，用于尿酸的检测。MnO 2纳米片具有一些有趣的物理化学性质，如高消光系数和丰富的氧化还原化学，这使它们成为一个优秀的传感平台。在MnO 2纳米片的存在下，由于内过滤效应以及其他猝灭机制，S，N-CD的荧光有效地关闭。通过向S，N-CDs-MnO 2纳米片溶液中加入尿酸，S，N-CDs的荧光由于其与MnO 2纳米片的反应而部分恢复。在最佳条件下，尿酸浓度在2.5 ~ 30 μ M范围内与荧光强度呈线性关系，检出限为0.8 μ M。方法用于生物样品的分析，结果令人满意。(C)2018爱思唯尔B. V.保留所有权利。
A turn-on fluorescent probe based on the effect of MnO2 nanosheets on the fluorescence of sulfur and nitrogen co-doped carbon dots (S,N-CDs) is reported for detection of uric acid. MnO2 nanosheets have several interesting physicochemical properties such as high extinction coefficient and rich redox chemistry, which make them an excellent sensing platform. The fluorescence of S,N-CDs efficiently turns off in the presence of MnO2 nanosheets due to the inner filter effect as well as other quenching mechanisms. By adding uric acid to the solution of S,N-CDs-MnO2 nanosheets, the fluorescence of S,N-CDs is partially recovered as a result of its reaction with MnO2 nanosheets. Under the optimum conditions, the recovered fluorescence intensity displays a linear relationship with the concentration of uric acid in the range of 2.5-30 mu M with a detection limit of 0.8 mu M. The method was applied for analysis of biological samples with satisfactory results. (C) 2018 Elsevier B.V. All rights reserved.