Efficient coding of cognitive variables underlies dopamine response and choice behavior.
Efficient coding of cognitive variables underlies dopamine response and choice behavior.
复制标题
认知变量的有效编码是多巴胺反应和选择行为的基础。
DOI：
10.1038/s41593-022-01085-7
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发表时间：
2022
影响因子：
25
通讯作者：
Machens,ChristianK
中科院分区：
文献类型：
--
作者：
Motiwala,Asma;Soares,Sofia;Atallah,BassamV;Paton,JosephJ;Machens,ChristianK
Reward expectations based on internal knowledge of the external environment are a core component of adaptive behavior. However, internal knowledge may be inaccurate or incomplete due to errors in sensory measurements. Some features of the environment may also be encoded inaccurately to minimize representational costs associated with their processing. In this study, we investigated how reward expectations are affected by features of internal representations by studying behavior and dopaminergic activity while mice make time-based decisions. We show that several possible representations allow a reinforcement learning agent to model animals’ overall performance during the task. However, only a small subset of highly compressed representations simultaneously reproduced the co-variability in animals’ choice behavior and dopaminergic activity. Strikingly, these representations predict an unusual distribution of response times that closely match animals’ behavior. These results inform how constraints of representational efficiency may be expressed in encoding representations of dynamic cognitive variables used for reward-based computations.
