Adenosquamous carcinoma of the colon and rectum
Adenosquamous carcinoma of the colon and rectum
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DOI：
10.1007/bf02055120
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发表时间：
1996-11-01
影响因子：
3.9
通讯作者：
RodriguezBigas, M
中科院分区：
文献类型：
--
作者：
Petrelli, NJ;Valle, AA;RodriguezBigas, M
目的：结肠和直肠的腺鳞癌是一种罕见的肿瘤。这些肿瘤具有恶性腺和鳞状成分，能够转移。我们报告七例结肠和直肠腺鳞癌患者及其临床结果。方法：回顾性分析了1971年至1994年在罗斯威尔公园癌症研究所肿瘤登记处发现的7例患者;结果：这些患者在我们机构的腺癌发病率为0.18%。有五个肿瘤位于直肠和两个在结肠。所有患者在就诊时均为III期或IV期。中位总生存期为23个月。在3例患者中，肿瘤与溃疡性结肠炎有关;其中1例患者存在高钙血症。Au患者死于他们的疾病或与疾病。结论：以前报道的这种癌症的侵袭行为在我们的系列中得到证实。
PURPOSE: Adenosquamous carcinomas of the colon and rectum are rare tumors. These tumors have malignant glandular and squamous components capable of metastasizing. We report seven patients with adenosquamous carcinoma of the colon and rectum and their clinical outcomes. METHODS: Retrospective review was undertaken of seven patients who were identified by the tumor registry at Roswell Park Cancer Institute between 1971 and 1994; RESULTS: These represent a 0.18 percent incidence of adenocarcinomas in our institution. There were five tumors located in the rectum and two in the colon. All patients were Stage III or IV on presentation. Median overall survival was 23 months. In three patients, the tumor was associated with ulcerative colitis; in one of these patients, hypercalcemia was present. AU patients died of their disease or with the disease. CONCLUSIONS: Previously reported aggressive behavior of this cancer is confirmed in our series.