Good school performance is a risk factor of suicide in psychoses:: a 35-year follow up of the Northern Finland 1966 Birth Cohort
Good school performance is a risk factor of suicide in psychoses:: a 35-year follow up of the Northern Finland 1966 Birth Cohort
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DOI：
10.1111/j.1600-0447.2006.00800.x
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发表时间：
2006-11-01
影响因子：
6.7
通讯作者：
Isohanni, M.
中科院分区：
文献类型：
--
作者：
Alaräisänen, A.;Miettunen, J.;Isohanni, M.
目的：我们的目的是分析1966年芬兰北部出生队列中良好的学校表现与自杀风险之间的关系，特别是在精神病患者中。方法：对11 017名年龄在16岁时存活的队列成员进行随访，随访至35岁。学校表现是通过综合学校结束时16岁的学校分数来衡量的。学校、诊断和死亡率数据基于国家登记册。结果：学业成绩优秀的精神病患者（最高20%）自杀校正风险比（HR）为3.56 (0.97-13.05)；因此，在非精神病人群中（97%没有精神病住院），调整后的HR为0.28（0.07-1.16）。即使校正了性别、社会阶层和发病年龄，相互作用（学校表现x精神诊断）仍显著（P = 0.01）。结论：在患有精神病的人群中，16岁时良好的学校表现与35岁前自杀风险的增加有关，而在没有患精神病的人群中，良好的学校表现与较低的自杀风险有关。
Objective: Our aim was to analyse the relationship between good school performance and risk of suicide in the Northern Finland 1966 Birth Cohort, especially in psychoses.Method: A total of 11 017 cohort members who were alive at the age of 16 years were followed up to the age of 35 years. School performance was measured by the school marks given at age 16 at the end of comprehensive school. School, diagnostic and mortality data were based on national registers.Results: For psychotic persons having good school performance (highest 20%), the adjusted hazard ratio (HR) for suicide was 3.56 (0.97-13.05) compared with the remaining 80%. In the non-psychotic population (97% without psychiatric hospitalization), accordingly, adjusted HR was 0.28 (0.07-1.16). Interaction (school performance x psychiatric diagnosis) was significant (P = 0.01) even when adjusted with gender, social class and age of onset of illness.Conclusion: Good school performance at age 16 years is associated with increased risk of suicide (before age 35 years) in persons who develop psychosis, whereas in persons who do not develop psychosis, it is associated with lower suicide risk.