Cyclization of 1,6-enynes with allylic chromate species
Cyclization of 1,6-enynes with allylic chromate species
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DOI：
10.1021/ol026362o
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发表时间：
2002-08-08
期刊：
影响因子：
5.2
通讯作者：
Oshima, K
中科院分区：
文献类型：
--
作者：
Nishikawa, T;Shinokubo, H;Oshima, K
[图解]用四甲基烯丙基铬酸盐处理1，6-烯炔类化合物时，会发生环化反应，同时引入甲基烯丙基。催化量的CrCl3和甲基烯丙基氯化镁也实现了这一环化过程。生成的环状金属有机物种在与亲电体反应时进一步官能化。
[GRAPHICS]Treatment of 1,6-enynes with tetramethallylchromate induces a cyclization reaction with concurrent introduction of a methallyl group. A catalytic amount of CrCl3 combined with methallyl magnesium chloride also achieves this cyclization process. The resultant cyclic organometallic species undergo further functionalization upon reaction with electrophiles.