Functions of N-acetylaspartate and N-acetylaspartylglutamate in brain: evidence of a role in maintenance of higher brain integrative activities of information processing and cognition.

Functions of N-acetylaspartate and N-acetylaspartylglutamate in brain: evidence of a role in maintenance of higher brain integrative activities of information processing and cognition.
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N-乙酰天冬氨酸和 N-乙酰天冬氨酰谷氨酸在大脑中的功能:在维持信息处理和认知的高级大脑整合活动中发挥作用的证据。

DOI:
10.1007/0-387-30172-0_7
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发表时间:
2006
影响因子:
--
通讯作者:
Guilfoyle,DavidN
Guilfoyle,DavidN
中科院分区:
医学4区
文献类型:
--
作者:
Baslow,MorrisH;Guilfoyle,DavidN

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大脑是一个复杂的信息处理器官,不能看、闻、听、尝或感觉。对于这些事情,它依赖于源自各种环境神经元传感器的有意义的编码电生理信号,如果没有这些信号的输入,正常的认知能力就无法维持。大脑对环境的新陈代谢生命线是血管系统,它依赖血管系统持续供应营养物质,并清除废物。因此,大脑和整个生物体的健康取决于它、环境传感器和血管系统之间的持续相互作用。叠加在基本的个体神经元对能量和废物清除的需求上,是一个非常复杂的神经网络,它接收、解释和响应来自外部和内部的大脑信息。在神经网络最集成的层面上,是具有更高认知功能的领域。
The brain is a complex information-processing organ that cannot see, smell, hear, taste or feel. For these things it relies on meaningful encoded electrophysiological signals that originate in a variety of environmental neuronal sensors and without which input, normal cognitive abilities cannot be sustained. The brain’s metabolic lifeline to the environment is the vascular system, upon which it relies for a continuous supply of nutrients, and for removal of waste products. Thus, the well being of both the brain and the whole organism depend on continuous interactions between it, its environmental sensors, and the vascular system. Superimposed on basic individual neuronal requirements for energy and waste product removal, is a very complex neuronal network that receives, interprets and responds to brain messages of both external and internal origin. At the most integrated level of neural networking is the realm of higher cognitive functions.